Concordant systemic and local eosinophilia relates to poorer disease control in patients with nasal polyps
نویسندگان
چکیده
منابع مشابه
Distinct characteristics of nasal polyps with and without eosinophilia.
INTRODUCTION Eosinophilic and noneosinophilic Nasal polyps (NPs) are different subtypes of NPs and require different treatment methods. OBJECTIVE To compare the histologic characteristics, mRNA and protein expression between Nasal Polyps with and without eosinophilia. METHODS NPs tissues were obtained from eighty-six NPs patients during surgery. Eosinophilic and noneosinophilic NPs were dis...
متن کاملT helper cell population and eosinophilia in nasal polyps.
OBJECTIVE To analyze the immunological pattern of nasal polyposis in patients with and without allergy, the percentages of CD4+ cells expressing intracellular interferon-gamma and interleukin-4 (T helper [T(H)] type 1 and 2 cells) were measured by flow cytometry in samples from patients with nasal polyps. METHODS Samples from 32 patients (16 atopic, 16 nonatopic) were studied. The fresh nasal...
متن کاملCutaneous reactivity pattern and nasal smear cytology in patients with chronic rhinosinusitis with nasal polyps; is it associated with the course of the disease?
Background and Objectives: To determine the association of hyper-reactivity to environmental allergens and mucosal secretion cytology with the course of disease in patients with chronic rhinosinusitis and nasal polyps (CRSwNP). Methods: A cross sectional study was conducted at Tehran Clinic of Asthma and Allergy in 2016. Adult patients who earned the definite diagnosis of CRSwNP and were free o...
متن کاملCould Eosinophilia predict clinical severity in nasal polyps?
BACKGROUND Although nasal polyps are one of the most frequent diseases, their etiopathogenesis remains unclear.Since eosinophils are the main inflammatory cells in the substantial proportion of nasal polyp tissues, they are considered potentially responsible for the etiopathogenesis and prognosis of the disease. Aim of this study was to investigate the relation between mucosal and peripheral eo...
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ژورنال
عنوان ژورنال: World Allergy Organization Journal
سال: 2019
ISSN: 1939-4551
DOI: 10.1016/j.waojou.2019.100052